(5-Chloro-2-methylphenyl)boronic acid

(5-Chloro-2-methylphenyl)boronic acid - Names and Identifiers

Name	5-chloro-2-methylphenylboronic acid
Synonyms	5-CHLORO-2-METHYLPHE 2-METHYL-5-CHLOROPHENYLBORONICACID 5-CHLORO-2-METHYLPHENYLBORONIC ACID 5-chloro-2-methylphenylboronic acid 5-Chloro-2-Methylphenyl boconic acid 5-CHLORO-2-METHYLBENZENEBORONIC ACID (5-Chloro-2-methylphenyl)boronic acid Boronic acid, B-(5-chloro-2-methylphenyl)- 5-Chloro-2-Methylphenylboronic Acid (contains varying aMounts of Anhydride)
CAS	148839-33-2
InChI	InChI=1/C7H8BClO2/c1-5-2-3-6(9)4-7(5)8(10)11/h2-4,10-11H,1H3

(5-Chloro-2-methylphenyl)boronic acid - Physico-chemical Properties

Molecular Formula	C7H8BClO2
Molar Mass	170.4
Density	1.26±0.1 g/cm3(Predicted)
Melting Point	162-166
Boling Point	328.0±52.0 °C(Predicted)
Flash Point	152.2°C
Vapor Presure	7.87E-05mmHg at 25°C
Appearance	Solid
pKa	7.63±0.58(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.549
MDL	MFCD03411939

(5-Chloro-2-methylphenyl)boronic acid - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36 - Irritating to the eyes R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. S60 - This material and its container must be disposed of as hazardous waste. S37 - Wear suitable gloves.
HS Code	29319090
Hazard Note	Irritant

(5-Chloro-2-methylphenyl)boronic acid - Introduction

acid is an organic compound with the chemical formula C7H7BClO2. The following is a description of its nature, use, preparation and safety information:

Nature: acid is an organic acid that is a white solid. It has strong corrosive and pungent odor.

Use:
acid is one of the commonly used reagents in the field of organic synthesis, which can be used as a catalyst, ligand and selective oxidant. It is often used in the synthesis of olefins, selective oxidation reactions and asymmetric catalytic reactions in organic synthesis.

Method:
The preparation of Ti acid can be obtained by the reaction of benzoic acid and boron dichloride in the presence of sodium carbonate. The specific preparation method is as follows:
1. Dissolve benzoic acid and sodium carbonate in water.
2. Add thionyl chloride as a solvent, stir well and reduce the temperature to below 0 ℃.
3. Slowly add boron dichloride and react for 2 hours.
4. Acidify the reaction solution to obtain acid.

Safety Information:
acid is irritating and corrosive, and contact with the skin, eyes and respiratory tract may cause severe irritation. Appropriate personal protective equipment, such as chemical protective gloves, protective glasses and protective masks, should be worn during operation. Keep away from open flames and heat sources, and avoid mixing with oxidizing agents and reducing agents during storage. At the same time, it should be stored in a sealed container, away from children, and avoid inhaling dust or solution. In case of abnormality, seek medical help immediately. The above are some common safety operation precautions, but they are not exhaustive. Please follow the more detailed chemical experiment operation specifications in the specific operation.

Last Update：2024-04-10 22:29:15